So I started my first cycle 3 weeks ago of only test e, and about 2 weeks in I suddenly had some of the worst anxiety of my life. It doesn't help that I work in a bar by the beach and have to deal with drunk assholes every night but I just noticed literally in about a days time, I dreaded the thought of going to work and was basically overwhelmed with nerves. It was so pathetic I felt literally like a little girl haha. I have had issues with anxiety in the past, but had no idea test would lead to the worst sudden anxiety I can remember experiencing; obviously, I thought it would do the exact opposite. So after reading into it a bit (but nearly stopping my first cycle) I assumed a spike in estrogen was the cause. So I went home and took about .33 mgs of Anastrozole (which I didn't really think I needed to take until several weeks in or until I had sensitive nipples) and within a few hours I was back to normal. It's been about a week since now and I'm having awesome gains and no mental issues but figured I'd share this and see if anyone else has had similar experiences to this since there is very little that I can find about juice causing anxiety online. Furthermore; mostly all I can find is to DEFINITELY avoid tren if you have any anxiety or similar issues. So in conclusion, I'd have to say that anastrozole or similar products should be taken from the START of the cycle to avoid complications down the road, but of course, everyone's body reacts differently, any input??