Sarms - Selective Androgen Recptor Modulators
Sarms, what exactly are they? Well their definition is as follows:
Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands. (The name follows the terminology currently used for similar molecules targeting the estrogen receptor, "selective estrogen receptor modulators," such as Tamoxifen.) They are intended to have the same kind of effects as androgenic drugs like anabolic steroids but be much more selective in their action, allowing them to be used for many more clinical indications than the relatively limited legitimate uses that anabolic steroids are currently approved for. (Definition source - Wikipedia)
SARMs have been studied and developed since 1998 but are still in developmental stages due to lack of research. There are no true sarms available on the legitimate pharmaceutical market however, Ostarine has made it into the third and last phase of clinical development but their actual effect on “Tissue Selective Activity” is still unknown. Research peptide forum is said to be the closest match to its true chemical composition.
So here we have a drug that very closely mimics the effects of anabolic steroids without the sides, sounds like a win-win situation. Well not exactly since there are very few studies that support this theory although you will find conflicting views from supplement marketers. This remains debatable so until new studies surface, we will just touch on the different types of sarms and what their intended effects are. I neither agree/disagree with the integrity of sarms or their proposed function, rather I am just simply defining what they are and what they are marketed for.
Sarms are uncharted waters for most and hopefully more feedback will surface as people become more familiar with their function.
All the information below has be obtained from the following website which I found to be most informative:
http://www.sarmsinfo.com/
The four sarms currently discussed are:
Andarine S4, GW1516 or GSK-516, LGD-4033, and Ostarine MK-2866
· Andarine S4 - The benefit of using Andarine S4 over anabolic steroids or testosterone is that you don’t have to worry about non-skeletal muscle tissues experiencing androgen activity. Andarine S4 is also used for various types of medical ailements. It may be prescribed to treat Bening Prostatic Hypertrophy, Muscle wasting, and Osteoporosis.
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· GW1516 or GSK-516 - A PPAR modulator allows the body to use more glucose and to create additional muscle tissue. One of the PPARs is GW-501516. It may be referred to as GW1516 or GSK-516 as well. It can help to reduce and even reverse various problems in men who are obese or that have symptoms of pre-diabetes due to problems with their metabolism. The use of GW-501516 may be a viable treatment for reducing obesity and various conditions that are linked to it.
· LGD-4033- One of the members of the Selective Androgen Receptor Modulator category, also known as SARM, is LGD-4033. It is an oral product that is non-steroidal, but it can offer many of the same benefits as some of the anabolic steroids. The use of LGD-4033 medically includes treatment of muscle wasting. This can be due to issues with cancer or muscle loss due to the natural aging process
· Ostarine MK-2866 - A type of SARM (short for Selective Androgen Receptor Modulator) is called Ostarine MK-2866. It is typically prescribed for the treatment and prevention of muscle wasting. Such health concerns can be genetic, due to HIV/AIDS, and other ailments. There are also studies in place that indicate this medication may soon be prescribed as part of hormone replacement therapy (HRT)