Hi Dolf, there was an article by Anthony Roberts which stated that Arimidex & Letro suffered reduced effectiveness when used with Nolvadex. In other words, Nolvadex will greatly decrease the blood plasma levels of them (*). That is why Arimidex/Letro if not often used in PCT as Aromasin is. Adex/Letro is commonly used on-cycle while Aro can be used both on-cycle and off-cycle. Nolva does not alter the pharmacokinetics of Aro but does alter it for Adex or Letro. Thus, many people are using a Nolva/Aro combo for PCT which is more effective at raising natty test levels than Nolva/Clomid is.
Does anyone agree or disagree with this? What are your thoughts?
(*)Reference:
J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):85-91
Does anyone agree or disagree with this? What are your thoughts?
(*)Reference:
J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):85-91