Guys - I have been doing research for months and months about Glucophage. I am not diabetic personally, but rather carb-sensitive. I believe at the root of this is mild Insulin Resistance which i take supplements like R-ALA, chromium, cinnamon,...etc and it works like a charm. My fasting morning glucose is ~ 84. My glucose read after (1.5 hours) an average meal (~ 30g crabs or so) is ~ 89 utilizing these supplements with meals ofcourse.
With post workout meals where i engage more carbs to spike insulin, i do get some bloating, and weight gain. So I've been thinking about adding metformin , maybe @ 850mg once a day with post workout meal (carb rich meal). On non-workout days, i'd take it with the heaviest carb meal. The reasoning here is to utilize Metformin's ability to sensitize the muscle tissues to absorb a bigger quantity of the glucose flowing in the blood & hence less glucose available in the bloodstream to flow to fat cells and get "stored" as fat.
This can be a huge help to consume more carbs and have more utility of the carbs ingested towards muscle than fat. From the experiments published online, i seen that Metformin has the ability to sensitize mostly skeletal muscle tissues to absorb more of the glucose.
I wonder about the negative sides of using metformin long periods of time at this dosage 850mg once a day everyday? Do i need to cycle on & off of it for safety reasons ?? I see too many conflicted opinions about this on forums online. I also see anecdotal writeups about metformin induced kidney problems, but havent seen it documented in any formal research. If its, please point me to it.
Please share your experience with Metformin - dosage, and regimn (cycle on/off or continuous use), timing,...etc. Would love to hear the MG community's experiences or research about this.