I was doing some searching around to further my understanding of glucose disposal, and hopefully add something of interest to the conversation. I found that perhaps there isn't necessarily a hierarchy of disposal (such as liver->skeletal muscle->adipose), but more of an allotment by percentage to various tissues. I have included a small excerpt and diagram from an in depth article discussing glucose disposal (which goes well beyond mere insulin. Other hormones involved are glucogon, cortisol, epinephrine, growth hormone, and FFA, or free fatty acids). For the purposes of explanantion, the diagram shows 100g of glucose ingested. First, the liver takes the full 100g, keeping 30g for a variety of purposes beyond mere storage. The liver then releases 70g to be delivered to other tissues and organs. 27g to muscle tissue, 15g to the brain, 8g to the kidneys, and 5g to adipose tissue. Thus, glucose disposal is a bit more complex than a hierarchical model. For the complete article click the link:
https://www.springer.com/cda/content/document/cda.../9780387098401-c1.pdf?
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